Fig. 3

The freeze-dried C. papaya leaf juice (FCPLJ) increased the monocyte chemoattractant protein 1 (CCL2/MCP-1) in the plasma of AG129 mice infected with dengue virus. The CCL/MCP-1 cytokine level in plasma collected from mock infected (white bars), infected (black bars) and infected + FCPLJ (checkered bars) AG129 mice groups at day 3, day 5 and day 7 post-infection were analyzed by Procartaplex immunoassay. Bars represent the mean values ± SEM. The cytokine level was compared between experimental groups using ANOVA multiple comparison test. a. CCL/MCP-1 level in plasma of AG129 mice treated with 500 mg/kg BW of FCPLJ. b. CCL/MCP-1 level in plasma of AG129 mice treated with 1000 mg/kg BW of FCPLJ. Astrisk (*) denotes as significant difference at P value < 0.05