Fig. 3From: Critical pharmacokinetic and pharmacodynamic drug-herb interactions in rats between warfarin and pomegranate peel or guava leaves extractsPercentage of CYP2C9 activity relative to untreated isolated hepatocytes of different groups treated with sulfamethoxazole (130 μg/ml) and warfarin (3 μg/ml) alone or in combination with: (a) pomegranate peel extract (120 μg/ml), ellagic acid (48 μg/ml) or, (b) guava leaves extract (294.1 μg/ml) and quercetin (15 μg/ml). Each data point represents the mean ± SD (n = 6). Statistical evaluation was performed by comparing the percentage of activity of untreated cells with treated cells *p < 0.05, **p < 0.01Back to article page