Combined antibacterial effect of essential oils from three most commonly used Ethiopian traditional medicinal plants on multidrug resistant bacteria

Table 2 Inhibition zone (mm) of essential oils against MDR bacteria at AAU, 2018

Medicinal plant	Con (μl/ml)	μl/disc	Gram positive		Gram negative
			MSSA	MRSA	E. coli		K. pneumoniae
			MSSA	MRSA	R	S	R	S
T.schimper	100	10	16 ± 0.9	16 ± 0.4	11 ± 0.4	10 ± 0.7	17 ± 0.4	17 ± 1.2
T.schimper	100	20	21 ± 0.6^*	21 ± 0.3	17 ± 0.4	13 ± 0.1	24 ± 0.2^#	24 ± 1.0
B. cuspidata	100	10	19 ± 0.3	19 ± 0.2	15 ± 1.3	11 ± 0.3	19 ± 0.3	18 ± 0.2
B. cuspidata	100	20	22 ± 0.6^*	25 ± 0.1	19 ± 0.8	15 ± 0.1	23 ± 0.3^#	23 ± 0.9
B. ogadensis	100	10	13 ± 0.8	12 ± 0.1	9 ± 0.2	8 ± 0.7	17 ± 0.9	17 ± 0.3
B. ogadensis	100	20	19 ± 0.8	17 ± 0.3	14 ± 0.2	14 ± 0.2	20 ± 0.6	21 ± 0.9
Positive control	Cefoxitin		S	R	–	–	–	–
	Gentamicin		–	–	R	S	R	S
	Ceftriaxone		–	–	R	S	R	S
Negative control (5% DMSO)			N	N	N	N	N	N

The values represent mean ± standard deviation, N NO inhibition zone, R Resistant (≤16 mm IZ), S Susceptible (≥ 21 mm IZ). Where, ^*P < 0.05when compared to cefoxitin treated MRSA. While, ^#P < 0.05 when compared to modern drug treated K. pneumoniae

ISSN: 2662-7671