Improvement of diabetic wound healing by topical application of Vicenin-2 hydrocolloid film on Sprague Dawley rats

Table 2 Histological features of wound healing

Histological score	0	1	2	3	4
Epidermal Regeneration	None	Mild	Moderate	Complete	–
Granulation tissue thickness	None	Mild	Moderate	Complete	–
Fibroblast proliferation	Absence	Occasional presence	Light scattering	Abundance	Confluence
Presence of neovascularization (angiogenesis)	Absence	Occasional presence	Light scattering	Abundance	Confluence
Presence of inflammatory cells	Absence	Occasional presence	Light scattering	Abundance	Confluence

(A modification of Altavilla et al. [25], Lee et al. [26] and Gopalakrishnan et al. [27])

ISSN: 2662-7671