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Fig. 8 | BMC Complementary and Alternative Medicine

Fig. 8

From: Bioassay-guided isolation of active anti-adipogenic compound from royal jelly and the study of possible mechanisms

Fig. 8

Schematic diagram on the molecular mechanism of the anti-adipogenic effect of 10-HDA in 3 T3-L1 preadipocytes. 10-HDA inhibited the accumulation of lipid droplets within 3 T3-L1 adipocyte via two possible mechanisms; by inhibiting cAMP/PKA pathway and p-Akt and MAPK dependent insulin signaling pathway. ATP: adenosine triphosphate; PKA: protein kinase A; MAPK: mitogen-activated protein kinase; ADIPOQ: adiponectin precursor gene; LPL: lipoprotein lipase; FFA: free fatty acids; TG: triacylglycerol

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