Skip to main content

Table 4 Effects of ChondroT on serum levels of Creatinine (Cr), blood urea nitrogen (BUN), glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) in hyperuricemic mice

From: Effects of ChondroT on potassium Oxonate-induced Hyperuricemic mice: downregulation of xanthine oxidase and urate transporter 1

Blood parameter

NC

HC

AP (mg/kg)

ChondroT (mg/kg)

5

37.5

75

150

Creatinine (mg/dL)

0.20 ± 0.02

0.75 ± 0.04 ###

0.23 ± 0.01 **

0.50 ± 0.04

0.28 ± 0.02 *

0.23 ± 0.02 **

BUN (mg/dL)

23.62 ± 0.56

40.10 ± 1.21 ###

21.45 ± 0.96 ***

26.27 ± 0.58 *

22.95 ± 1.06 *

20.43 ± 0.74 ***

GOT (U/L)

48.67 ± 0.90

73.33 ± 3.95 ##

39.80 ± 0.92 ***

54.83 ± 1.90 *

46.00 ± 2.01 *

39.75 ± 2.56 **

GPT (U/L)

15.00 ± 1.58

28.00 ± 1.46

13.50 ± 0.91 *

24.17 ± 0.95

20.33 ± 1.29

15.00 ± 1.39 *

  1. NC, normal control; HC, hyperuricemic control with potassium oxonate (300 mg/kg); AP, allopurinol (5 mg/kg). Values are mean ± standard error (S.E., n = 5). ##P < 0.01 and ###P < 0.001 compared with NC group; *P < 0.05, **P < 0.01, and ***P < 0.001 compared with HC group