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Table 4 Effects of ChondroT on serum levels of Creatinine (Cr), blood urea nitrogen (BUN), glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) in hyperuricemic mice

From: Effects of ChondroT on potassium Oxonate-induced Hyperuricemic mice: downregulation of xanthine oxidase and urate transporter 1

Blood parameter NC HC AP (mg/kg) ChondroT (mg/kg)
5 37.5 75 150
Creatinine (mg/dL) 0.20 ± 0.02 0.75 ± 0.04 ### 0.23 ± 0.01 ** 0.50 ± 0.04 0.28 ± 0.02 * 0.23 ± 0.02 **
BUN (mg/dL) 23.62 ± 0.56 40.10 ± 1.21 ### 21.45 ± 0.96 *** 26.27 ± 0.58 * 22.95 ± 1.06 * 20.43 ± 0.74 ***
GOT (U/L) 48.67 ± 0.90 73.33 ± 3.95 ## 39.80 ± 0.92 *** 54.83 ± 1.90 * 46.00 ± 2.01 * 39.75 ± 2.56 **
GPT (U/L) 15.00 ± 1.58 28.00 ± 1.46 13.50 ± 0.91 * 24.17 ± 0.95 20.33 ± 1.29 15.00 ± 1.39 *
  1. NC, normal control; HC, hyperuricemic control with potassium oxonate (300 mg/kg); AP, allopurinol (5 mg/kg). Values are mean ± standard error (S.E., n = 5). ##P < 0.01 and ###P < 0.001 compared with NC group; *P < 0.05, **P < 0.01, and ***P < 0.001 compared with HC group