Fig. 6

The treatment of DBT mitigates Aβ-triggered caspase 3/9 levels. Cultured cortical neurons were co-treated with a series amount of DBT (DBT-L: 12.5 μg/mL; DBT-H: 100 μg/mL) and Aβ (20 μM) for 48 h. Then cells were labeled with caspase 3/9 detection kit and Hoechst for 30 min. The activities of caspase 3/9 were evaluated by measuring the fluorescence intensity. Micrographs were taken by a confocal microscope