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Table 2 Characteristics of Included Studies

From: The impact of peppermint oil on the irritable bowel syndrome: a meta-analysis of the pooled clinical data

Year

Author

Country

Design

Setting

N Enrolled

N Completed

Duration of therapy

2013

Alam

Bangladesh

Double-Blind RCT

University Single-Center

74

65

6 weeks

2016

Cash

USA

Double-Blind RCT

Multicenter

72

70

4 weeks

2005

Capanni

Italy

Double-Blind RCT

University Single-Center

178

173

12 weeks

2007

Cappello

Italy

Double-Blind RCT

University Single-Center

57

50

4 weeks

1989

Carling

Sweden

Double-blind Cross Over 3-arm RCT 1-Week Washout

2 University Centers

40

38

2 weeks

1984

Dew

Wales

Double-Blind Cross Over Washout Period

Multicenter

29

29

2 weeks

1988

Lech

Dutch

Double-Blind RCT

University Single-Center

47

42

4 weeks

1997

Liu

China

Double-Blind RCT

University Single-Center

110

101

4 weeks

2009

Merat

Iran

Double-blind RCT

University Single- Center

90

60

8 weeks

1979

Rees

UK

Double-Blind Cross Over Washout Period Defined by Recurrence of Active Symptoms

University Single- Center

18

16

3 weeks

1990

Schneider

USA

Double-blind Cross Over RCT

2-Week Washout

University Single- Center

60

47

6 weeks

1988

Weiss

Germany

Single blinded, RCT

Hospital, single center

60

46

3 weeks