Fig. 3

Plasma cytokine variations measured at T1, T2 and T3. Cytokines were determined using a 13-plex mouse bead immunoassay kit. Levels of IL-2 (a), IL-4 (b), IL-8 (c), IL-12 (d), IL-17A (e), IFN-γ (f), MIP-1β (g) and MCP-1 (h) are shown for the whole IBS cohort and for IBS subtypes. Data are expressed as mean ± SD of at least three replicates. Calculated P values were corrected for multiple comparisons by using the Benjamini-Hochberg method. *P < 0.05 if compared to T1