Fig. 3From: Celastrus orbiculatus extracts induce apoptosis in mTOR-overexpressed human hepatocellular carcinoma HepG2 cellsEffects of COE on cellular morphology of the HCC cells. The HepG2/mTOR+ cells were treated with 0.1%DMSO as solvent control, or 2 mg/L DDP, or different concentrations of COE (20, 40, and 80 mg/L) for 24 h. a and b the HepG2/mTOR+ cells were observed under inverted microscope and taken phase-contrast images from the same fields (100×). c the morphological changes were observed under transmission electron microscope (2950×, Scale, 1 μm); red arrows are representative of the apoptotic bodies. (**P < 0.01, ***P < 0.001, compared with the vehicle)Back to article page