Fig. 1

Typical LC-MS chromatogram of JPYSF. a Structures of chemical markers analyzed in JPYSF extract, including sodium danshensu (1), salvianolic acid B (2), echinacoside (3), liquiritin (4), acteoside (5), calycosin 7-O-β-glucoside (6), astragaloside IV (7), formononetin (8), and hesperidin (internal standard, ISTD). b The representative LC-MS chromatograms of mixed standards and JPYSF extract. The LC condition was described in the Methods. The denotations from 1 to 8 in the chromatogram correspond to the chemical markers as shown in (a). The identification of the chemical markers was determined by a MS detector in a negative mode except astragaloside IV (7) in a positive mode. Representative chromatograms were shown, n = 3