Table 1 Compounds identification of freeze-dried C. papaya leaf juice by UPLC-HRAMS analysis

1

*Quinic acid

C₇H₁₂O₆

0.46

Negative

91.05545/2.28

102.94775, 127.04004 (100)

2

*Malic Acid

C₄H₆O₅

0.51

Negative

133.01434/1.19

115.00343 (100), 71.01169, 89.02279, 75.00661

3

*Protocatechuic acid

C₇H₆O₄

0.81

Negative

153.01880/3.69

109.02846 (100), 111.101892 (10)

4

*Chlorogenic acid

C₁₆H₁₈O₉

1.41

Negative

353.08746/2.13

191.01953(100)

5

*p-Coumaric acid

C₉H₈O₃

2.63

Positive

165.05493/1.87

147.04439 (100), 149.04929 (30), 119.04953 (20) 142.96738

6

*Caffeic acid

C₉H₈O₄

3.08

Negative

179.03476/2.26

135.04527 (100), 136.98357 (10)

7

**Manghaslin

C₃₃H₄₀O₂₀

4.66

Negative

755.20654/4.79

300.02884 (100), 301.03391 (40), 271.02570, 151.00323

8

**Clitorin

C₃₃H₄₀O₁₉

4.74

Negative

739.20807/0.09

284.03326 (100), 285.03860 (50), 255.09275, 151.00337

9

**Sinapic acid

C₁₁H₁₂O₅

4.77

Negative

223.06154/1.44

164.04741 (100), 149.02414 (80), 208.03912 (70), 170.07121 (20)

10

**Isoquercetin

C₂₁H₂₀O₁₂

4.83

Negative

463.09009/2.99

300.02841 (100), 301.03516 (60), 271.02573, 402.06155

11

*Ferulic Acid

C₁₀H₁₀O₄

4.89

Negative

193.05016/3.24

134.03703 (100), 178.02638 (30), 149.06056 (10)

12

*Rutin

C₂₇H₃₀O₁₆

4.94

Negative

609.14673/2.82

300.02887 (100), 301.0583 (80) 302.03983, 151.00136

13

**Astragalin

C₂₁H₂₀O₁₁

4.99

Negative

447.09494/2.75

284.03329 (100), 285.03998 (80), 255.03046 (20), 327.05276,

14

*Nicotiflorin

C₂₇H₃₀O₁₅

5.04

Negative

593.14807/2.65

238.18059 (100), 256.191689 (20),137.09636

15

**Dehydrocarpaine II

C₂₈H₄₈N₂O₄

5.20

Positive

475.35425/2.34

284.03308 (50), 285.03891 (100), 273.11279, 151.00275

16

**Dehydrocarpaine I

C₂₈H₄₈N₂O₄

5.27

Positive

477.37003/2.82

240.19635 (50), 220.16989, 256.19165

17

*Myricetin

C₁₅H₁₀O₈

5.31

Negative

317.03104 /4.82

178.9979 (80), 151.00313 (60)

18

**Carpaine

C₂₈H₅₀N₂O₄

5.45

Positive

479.38556/2.56

240.19623 (100), 241,19969, 222.18558

19

*Fisetin

C₁₅H₁₀O₆

5.78

Negative

285.0405/3.98

163.00359 (40), 135.00841 (30) 121.0912 (20)

20

*Morin

C₁₅H₁₀O₇

6.10

Negative

301.03564/4.52

151.00308 (100), 229.05057 (20)

21

*Quercetin

C₁₅H₁₀O₇

6.94

Negative

301.03571/4.75

151.00320 (100), 178.99736 (50), 273.04007 (20), 257.04529 (20)

22

*Kaempferol

C₁₅H₁₀O₆

7.47

Negative

285.04041/3.67

151.00298 (100), 229.9550

23

* Citropten

C₁₁H₁₀O₄

7.78

Positive

207.06567/2.34

192.04166, 163.07509 (100)

24

*Isorhamnetin

C₁₆H₁₂O₇

7.84

Negative

315.0517/4.34

300.02762 (100), 151,00200 (10)