Fig. 5
An independent experiment showing that 1000 mg/kg BW freeze-dried C. papaya leaf juice was not affecting plasma NS1 and viral RNA levels in AG129 mice during dengue infection. (a) AG129 mice infected with dengue virus strain NGC (2 X 106 PFU) were treated with 1000 mg/kg BW of freeze-dried CPLJ daily from day 1 to day 3 post infection. The plasma NS1 level of mock infected (black circles) (n=5), infected (red squares) (n=5) and infected+CPLJ 1000 (green triangles) (n=5) AG129 mice groups were detected on day 3, 5 and 7 by NS1 antigen immunoassay. (b) The plasma viral RNA of infected (red squares) (n=5) and infected+CPLJ 1000 (green triangles) (n=5) AG129 mice groups were detected by quantitative reverse transcription PCR on day 3 and day 5 post infections. Data represent mean values ± SD