Fig. 3
The effect of freeze-dried CPLJ on the level of NS1 and viral RNA. AG129 mice inoculated with (a) 2X105 PFU and (b) 2X106 PFU dengue virus strain NGC were treated with 500 mg/kg BW of freeze-dried CPLJ once a day from day 1 to day 3 post infection. The NS1 levels in plasma of mock infected (black circles) (n=5), infected (red squares) (n=5) and infected+CPLJ 500 (green triangles) (n=5) AG129 mice groups were detected on day 1, 3 and 5 by NS1 antigen immunoassay. (c) The plasma viral RNA of infected (red squares) (n=5) and infected+CPLJ 500 (green triangles) (n=5) AG129 mice groups (2X106 PFU) were detected by quantitative reverse transcription PCR on day 3 and day 5 post infections. Data represent mean values ± standard deviations (SD)