Determination of the volatile and polyphenol constituents and the antimicrobial, antioxidant, and tyrosinase inhibitory activities of the bioactive compounds from the by-product of Rosa rugosa Thunb. var. plena Regal tea

Table 4 MIC and MBC or MFC of RFCS and different monomers against pathogenic bacteria (μg/mL)

Compound	L. ivanovii		S. enteritidis enteritidis		S. aureus		E. coli		C. albicans		P. acnes		F. nucleatum
	MIC	MBC	MIC	MBC	MIC	MBC	MIC	MBC	MIC	MFC	MIC	MBC	MIC	MBC
RFCS	500	> 1000	500	> 1000	125	1000	500	1000	1000	> 1000	125	500	64	250
Linalool	500	> 1000	500	> 1000	250	1000	250	1000	250	1000	250	1000	250	1000
Phenylethyl alcohol	250	500	125	500	125	250	250	1000	250	500	125	500	8	32
Citronellol	250	500	250	1000	125	500	250	500	250	500	125	500	250	1000
α-bisabolol	8	32	500	> 1000	250	1000	500	1000	1000	> 1000	125	500	8	32
Hyperoside	250	500	250	500	250	1000	250	1000	250	1000	250	1000	250	500
Kaempferol-3-O-rutinosid	500	1000	500	> 1000	250	1000	500	> 1000	250	1000	500	1000	500	> 1000
Rutin	500	1000	125	500	250	500	250	1000	500	1000	125	250	62	500
Luteolin	500	1000	250	1000	500	> 1000	250	1000	250	500	250	500	125	500
Miconazole Nitrate	–	–	–	–	–	–	–	16	8	–	–	–	–	–
Hydrochloride tetracycline	< 0.1	< 0.1	8	16	16	16	16	–	–	16	8	16	2	2

Data are expressed as mean ± standard deviation of triplicate samples
MIC minimum inhibitory concentration, MBC minimum bactericidal concentration, MFC minimum Fungicidal concentration, RFCS rose flower cell sap, L. ivanovii Listeria ivanovii, S. enteritidis subspecies enteritidis: Salmonella enteritidis enteritidis, S. aureus Staphylococcus aureus, E. coli Escherichia coli, C. albicans Candida albicans, P. acnes Propionibacterium acnes, F. nucleatum Fusobacterium nucleatum

ISSN: 2662-7671