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Fig. 6 | BMC Complementary and Alternative Medicine

Fig. 6

From: Baicalin promotes apoptosis and inhibits proliferation and migration of hypoxia-induced pulmonary artery smooth muscle cells by up-regulating A2a receptor via the SDF-1/CXCR4 signaling pathway

Fig. 6

Proliferation and migration ability of PASMCs under different concentration of SDF-1 detected by CCK-8 and Transwell assay. a: Proliferation abilities increased with the increase of SDF-1 concentration. b: Migration abilities increased with the increase of SDF-1 concentration. c: Blockage of SDF-1/CXCR4 axis alters cell cycle distribution. d: Blockage of SDF-1/CXCR4 axis attenuates apoptosis-resistance in hypoxic PASMCs. # P < 0.05, ##p < 0.01 vs normoxia group, * P < 0.05 **P < 0.01 vs hypoxia group; + p < 0.05, ++ p < 0.01 Comparison between groups. n = 3

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