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Table 1 Body weight gain in sham-operated and OVX mice

From: Anti-osteoporotic effects of mixed compositions of extracellular polymers isolated from Aureobasidium pullulans and Textoria morbifera in ovariectomized mice

Periods

Groups

Body weights (g)

Body weight gains (g)

At OVX

[A]*

At 34 days after OVX [B]

At initial treatment [C]*

At sacrifice

[D]*

OVX recovery

[B-A]

Treatment

[D-C]

Controls

 Sham

25.55 ± 1.62

33.86 ± 2.53

29.90 ± 2.56

31.45 ± 2.74

8.31 ± 1.88

1.46 ± 0.92

 OVX

25.51 ± 1.20

37.40 ± 3.22b

33.96 ± 2.84a

37.59 ± 2.75a

11.89 ± 2.90a

3.63 ± 0.73a

Reference (2.5 mg/kg)

 RES

26.29 ± 0.80

36.68 ± 1.71b

33.40 ± 1.68b

35.75 ± 2.80a

10.39 ± 1.53b

2.35 ± 2.11

Single formula (200 mg/kg)

 EAP

26.61 ± 1.59

37.70 ± 3.22a

34.00 ± 2.62a

35.08 ± 1.90a

11.09 ± 3.11b

1.08 ± 1.76c

 TM

25.99 ± 1.35

37.31 ± 3.20b

34.10 ± 2.99a

35.06 ± 2.57a

11.33 ± 2.55 a

0.96 ± 0.78c

Mixed formula - EAP:TM (200 mg/kg)

 1:1

25.60 ± 1.82

36.59 ± 1.87

33.18 ± 1.83b

34.53 ± 2.11bd

10.99 ± 2.10a

1.35 ± 1.47c

 1:3

26.80 ± 2.21

37.63 ± 3.03a

34.26 ± 2.74a

35.24 ± 3.58a

10.83 ± 2.29b

0.98 ± 1.41c

 1:5

25.60 ± 1.01

37.58 ± 2.92b

33.80 ± 2.63a

34.69 ± 3.91bd

11.98 ± 3.34a

0.89 ± 2.03c

 1:7

26.73 ± 1.88

37.49 ± 2.95b

33.84 ± 2.53a

34.91 ± 2.49b

10.79 ± 2.27b

1.08 ± 2.23c

 1:9

26.39 ± 1.14

37.55 ± 2.98b

34.08 ± 2.67a

35.23 ± 1.75a

11.16 ± 2.53a

1.15 ± 1.73c

 3:1

25.93 ± 1.27

37.51 ± 2.99b

33.79 ± 2.76a

32.76 ± 2.66c

11.59 ± 2.83a

- 1.03 ± 1.43acef

 5:1

26.13 ± 1.24

37.54 ± 2.87b

34.00 ± 2.75a

34.99 ± 2.52b

11.41 ± 3.27a

0.99 ± 1.92c

 7:1

26.11 ± 0.96

37.48 ± 2.89b

33.96 ± 2.69a

34.91 ± 3.10b

11.36 ± 2.62a

0.95 ± 1.25c

 9:1

26.44 ± 1.66

37.50 ± 2.80b

34.05 ± 2.79a

35.05 ± 2.15a

11.06 ± 2.50a

1.00 ± 1.71c

  1. OVX Bilateral ovariectomy, RES Risedronate sodium, EAP Exopolymers purified from A. pullulans SM2001, TM T. morbifera leaf extracts, (EAP:TM) Mixed formula consisted of EAP and TM (g/g)
  2. Values are expressed mean ± S.D. of eight mice
  3. *All animals were overnight fasted
  4. ap < 0.01 and bp < 0.05 as compared with sham control by LSD test
  5. cp < 0.01 and dp < 0.05 as compared with OVX control by LSD test
  6. ep < 0.05 as compared with EAP single formula treated mice by LSD test
  7. fp < 0.05 as compared with TM single formula treated mice by LSD test