Fig. 4

The effects of SC on (a) NF-κB and IκB-α, and (b) MAPKs pathway-related protein expressions in RANKL-stimulated RAW 264.7 cells. RAW 264.7 cells were cultured in the presence of RANKL with the vehicle or SC. After 7 days, total protein was then isolated and protein expression levels were evaluated by Western blot assay. Data are represented as the means ± S.E.M. of three independent experiments. ^### p < 0.001 compared with non-treated cells. ^* p < 0.05 and ^*** p < 0.001 compared with only RANKL-treated cells