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Table 1 Antimicrobial activities of extracts, isolated compounds and reference antimicrobial drugs

From: Antimicrobial activities of flavonoid glycosides from Graptophyllum grandulosum and their mechanism of antibacterial action

Extracts/Compounds

Inhibition parameters

V. cholerae SG24 (1)

V. cholerae CO6

V. cholerae NB2

V. cholerae PC2

S. aureus ATCC 25923

C. albicans ATCC 9002

C. neoformans IP95026

MeOH extract

MIC

512

512

256

512

256

> 2048

> 2048

MMC

512

512

512

1024

512

/

/

MMC/MIC

1

1

2

2

2

/

/

n-BuOH extract

MIC

256

256

128

128

128

2048

2048

MMC

256

256

128

256

128

> 2048

> 2048

MMC/MIC

1

1

1

2

1

/

/

EtOAc extract

MIC

64

128

64

64

64

1024

512

MMC

128

128

64

64

64

1024

1024

MMC/MIC

2

1

1

1

1

1

2

 1

MIC

16

8

8

8

4

32

8

MMC

16

8

16

8

8

64

8

MMC/MIC

1

1

2

1

2

2

1

 2

MIC

16

16

8

8

4

64

16

MMC

32

16

16

8

8

64

32

MMC/MIC

2

1

2

1

2

1

2

 3

MIC

32

64

32

32

8

32

16

MMC

64

128

32

64

16

32

16

MMC/MIC

2

2

1

2

2

1

1

 4

MIC

8

8

8

8

4

8

4

MMC

16

8

8

8

4

8

8

MMC/MIC

2

1

1

1

1

1

2

 5

MIC

32

16

16

16

8

64

32

MMC

32

16

16

16

8

128

64

MMC/MIC

1

1

1

1

1

2

2

Refa

MIC

32

4

16

16

0.5

0.5

0.25

MBC

32

4

16

16

0.5

0.5

0.25

MBC/MIC

1

1

1

1

1

1

1

  1. /: not determined; MIC Minimum Inhibitory Concentration, MMC Minimum Microbicidal Concentration; the MIC and MMC were measured in μg/mL; a: amphotericin B for yeasts and ciprofloxacin for bacteria