Phytochemical analysis and evaluation of the cytotoxic, antimicrobial and antioxidant activities of essential oils from three Plectranthus species grown in Saudi Arabia

Table 3 Minimal inhibitory concentrations (MIC), minimal bactericidal concentration (MBC) and minimal fungicidal concentration (MFC) of the essential oils of Plectranthus species (mg/mL)

Microorganisms		Activity	P. cylindraceus	P. asirensis	P. barbatus	RA^a	RA^b
Bacteria	B. subtilis	MIC	0.275	0.275	0.275	7.8	NT
	B. subtilis	MBC	0.55	0.55	0.55	15.6	NT
	S. mutans	MIC	1.10	2.20	1.10	7.8	NT
	S. mutans	MBC	2.20	4.40	2.20	15.6	NT
	B. laterosporus	MIC	0.137	0.275	0.137	3.9	NT
	B. laterosporus	MBC	0.275	0.55	0.275	7.8	NT
	S. typhi	MIC	0.275	0.55	0.137	3.9	NT
	S. typhi	MBC	0.55	1.10	0.275	7.8	NT
Fungi	C. albicans	MIC	0.55	2.20	0.55	NT	3.5
	C. albicans	MFC	1.10	4.40	1.10	NT	7.0
	C. neoformans	MIC	0.275	0.275	0.275	NT	3.5
	C. neoformans	MFC	0.55	0.55	0.55	NT	7.0

B. subtilis: Bacillus subtilis ATCC 6633, S. mutans: Streptococcus mutans ATCC 25175, B. laterosporus: Brevibacillus laterosporus wild strain, Salmonella typhi wild strain, C. albicans: Candida albicans ATCC 60193 and C. neoformans: Cryptococcus neoformans wild strain, RA^a, Reference antibiotic (Gentamycin), RA^b Reference antibiotic (Nystatin). Values are given as mg/ml for essential oils and μg/ml for standard antibiotics, NT not tested

ISSN: 2662-7671