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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: Dendritic cells pulsed with generated tumor cell lysate from Phyllanthus amarus Schum. & Thonn. induces anti-tumor immune response

Fig. 4

Upregulation in the phenotypic expression of maturation markers in tumor lysate-pulsed dendritic cells. a Flow cytometric analysis of phenotypic HLA-DR, HLA-I, CD 83, 86 and CD 11c expression in (a) unloaded immature DCs, HCT-116-TLY-DCs at (b) 1:1, (c) 1:3 ratios, MCF-7-TLY at (d) 1:1, (e) 1:3 ratios, and (f) LPS-stimulated-only DCs. b The statistically transformed data show the significant increase in the expression levels of the maturation markers HLA-I, CD 83, 86 and CD 11c in tumor lysate pulsed dendritic cells over immature non-pulsed DCs (* P < 0.05) and LPS-only stimulated DCs (#P < 0.05). The data are representative of three experiments comprising three different healthy donors and analyzed by one-way ANOVA followed by Dunnett’s test. iDCs, immature dendritic cells; TLY, tumor lysate; LPS, Lipopolysaccharide

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