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Table 3 Effect of tocotrienol supplementation on blood parameters in postmenopausal osteopenic women

From: A 12-week evaluation of annatto tocotrienol supplementation for postmenopausal women: safety, quality of life, body composition, physical activity, and nutrient intake

Variable

Week 0

Week 6

Week 12

Overall P Value

Placeboa

Low TT

High TT

Placebo

Low TT

High TT

Placebo

Low TT

High TT

 

AST (U/L)

23.01 (10.68)

20.76 (6.57)

20.77 (4.95)

21.46 (5.53)

20.76 (6.76)

22.07 (7.97)

21 (5.23)

20.21 (9.39)

21.9 (7.63)

0.515

ALT (U/L)

23.75 (11.49)

19.9 (8.35)

19.03 (7.83)

20.82 (8.77)

19.66 (8.88)

20.5 (10.34)

21.14 (8.67)

18.72 (8.65)

19.57 (10.76)

0.494

Bilirubin (mg/dL)

0.53 (0.19)

0.52 (0.14)

0.57 (0.15)

0.46 (0.21)

0.48 (0.13)

0.43 (0.11)

0.5 (0.19)

0.47 (0.15)

0.47 (0.12)

0.583

ALP (U/L)

72.75 (14.68)

79.59 (15.53)

79.23 (22.96)

74.04 (16.95)

76.28 (18.04)

75.23 (16.56)

74.64 (15.6)

75.14 (16.31)

74.4 (16.99)

0.730

BUN (mg/dL)

14.46 (3.48)

16.41 (4.6)

16.57 (4.26)

14.86 (3.33)

15.62 (3.53)

17.07 (4.18)

15.54 (3.96)

16.97 (3.74)

16.67 (4.44)

0.120

Creatinine (mg/dL)

0.79 (0.12)

0.85 (0.13)

0.83 (0.12)

0.82 (0.12)

0.87 (0.15)

0.86 (0.15)

0.82 (0.13)

0.89 (0.17)

0.83 (0.12)

0.111

Ca (mg/dL)

9.62 (0.38)

9.54 (0.37)

9.48 (0.29)

9.44 (0.35)

9.41 (0.36)

9.37 (0.39)

9.57 (0.34)

9.55 (0.53)

9.5 (0.28)

0.607

Na (mmol/L)

138.86 (3.43)

139.72 (1.56)

139.27 (2.33)

139.5 (2.85)

140.03 (2.5)

140.1 (2.17)

139.75 (1.9)

140.48 (2.35)

140.37 (2.51)

0.346

K (mmol/L)

3.99 (0.28)

4.03 (0.36)

4.02 (0.35)

3.83 (0.24)

3.77 (0.29)

3.78 (0.4)

3.84 (0.32)

3.91 (0.31)

3.79 (0.39)

0.986

Cl (mmol/L)

103.71 (3.55)

104.1 (2.55)

104.1 (2.92)

103.61 (2.81)

103.55 (2.32)

104.5 (1.87)

103.29 (2.68)

103.9 (3.02)

104.13 (3.04)

0.314

CO2 (mmol/L)

21.68 (2.28)

22.48 (2.29)

22.87 (2.61)

19.79 (2.22)

21.1 (1.97)

20.83 (2.35)

20.89 (1.83)

21.45 (1.74)

20.67 (2.92)

0.086

Glucose (mg/dL)

90.61 (10.78)

88.21 (13.91)

85.8 (15.05)

87.43 (11.81)

83.34 (12.29)

83.27 (14.1)

84.75 (11.78)

83.83 (12.74)

83.83 (11.75)

0.282

Protein, total (g/dL)

7.19 (0.41)

7.23 (0.48)

7.17 (0.54)

7.2 (0.37)

7.24 (0.4)

7.2 (0.45)

7.29 (0.33)

7.24 (0.44)

7.31 (0.41)

0.810

Albumin (g/dL)

4.39 (0.26)

4.36 (0.21)

4.35 (0.26)

4.32 (0.24)

4.28 (0.2)

4.26 (0.18)

4.41 (0.19)

4.33 (0.21)

4.38 (0.19)

0.474

Globulin (g/dL)

2.8 (0.35)

2.87 (0.41)

2.82 (0.45)

2.89 (0.3)

2.97 (0.41)

2.95 (0.39)

2.87 (0.28)

2.91 (0.37)

2.94 (0.38)

0.468

Albumin/globulin

1.59 (0.22)

1.55 (0.25)

1.59 (0.26)

1.52 (0.19)

1.48 (0.23)

1.46 (0.21)

1.55 (0.16)

1.52 (0.2)

1.52 (0.22)

0.451

  1. aValues are mean(SD). AST asparate aminotransferase, ALT alanine aminotransferase, ALP alkaline phosphatase, BUN blood urea nitrogen, Ca calcium, Cl chloride, CO2 carbon dioxide, K potassium, Na sodium