Variables | Placebo | Low TT | High TT | P value |
---|---|---|---|---|
Number | 28 | 29 | 30 | Â |
Age [y] | 59.4±6.3 | 58.5±6.7 | 61.2±7.2 | 0.431 |
Weight [kg] | 74.3±17.9 | 76.3±14.8 | 74.3±16.8 | 0.680 |
Height [cm] | 160.0±6.2 | 163.7±6.5 | 155.6±27.1 | 0.107 |
Body mass index [kg/m2] | 28.9±6.5 | 28.5±5.0 | 28.8±5.8 | 0.986 |
Bone mineral density [T-score] | ||||
 Femoral Neck | −1.66±0.65 | −1.52±0.82 | −1.34±1.17 | 0.795 |
 Trochanter | −1.06±0.95 | −1.04±0.79 | −0.85±1.30 | 0.945 |
 Total spine | 0.79±0.89 | −0.87±0.85 | −0.53±1.10 | 0.654 |
 L1-L4 | −0.67±0.99 | −0.72±1.17 | 0.59±1.23 | 0.919 |
Serum 25 (OH)D [ng/mL] | 35.79±9.13 | 35.45±9.70 | 34.27±9.97 | 0.634 |
Serum TSH [mIU/L] | 2.25±1.01 | 2.45±1.46 | 2.52±1.71 | 0.944 |
Serum HbA1c [%] | 5.66±0.35 | 5.81±0.34 | 5.56±0.36 | 0.011 |
Medical history [n (%)] | ||||
 Broken bone as adult | 6 (21.43) | 7 (24.14) | 8 (26.67) | 0.897 |
 Osteoarthritis | 3 (12.00) | 5 (20.83) | 3 (11.54) | 0.584 |
 Diabetes | 2 (7.14) | 2 (6.90) | 0 (0.00) | 0.331 |
 Asthma | 4 (14.29) | 3 (10.34) | 2 (6.67) | 0.636 |
 Use of HRT in the past 2 yr | 10 (35.71) | 8 (27.59) | 6 (20.00) | 0.409 |
 Steroid or glucocorticoid use | 5 (17.86) | 4 (13.79) | 3 (10.00) | 0.687 |
 Prescribed osteoporosis drugs | 1 (3.57) | 4 (13.79) | 7 (23.33) | 0.093 |