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Table 4 Antinociceptive activity of P. racemosa leaves AME and aspirin on acetic acid induced writhing in mice

From: Phenolic profile, anti-inflammatory, antinociceptive, anti-ulcerogenic and hepatoprotective activities of Pimenta racemosa leaves

Groups

Dose mg/kg b.wt.

Number of writhing / 30 min (X ± S. E)

% Inhibition of writhing

Potency

Saline

1 ml

15 ± 1.14

–

Aspirin

200

5 ± 0.44*

66.66

1

AME

175

12.2 ± 0.58*@

18.66

0.28

350

9 ± 0.31*@#

40

0.6

700

7.6 ± 0.4*@#

49.33

0.74

  1. Data represent the mean value ± S.E; n = 5
  2. *Significant different from saline control group at P ≤ 0.05; @ Significant different from aspirin group a P ≤ 0.05,# Significant difference from the extract 175 mg/kg b.wt. group a P ≤ 0.05; Potency was calculated as regard the percentage change of the aspirin