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Table 1 The characteristics, intervention, and outcome of HFMD cases (2008–2016) $

From: Hand-foot-mouth disease and use of steroids, intravenous immunoglobulin, and traditional Chinese herbs in a tertiary hospital in Shantou, China

 

Total

Mild cases

Severe cases

Very severe cases

N = 3778

n = 2208

n = 1566

n = 4

Gender

Male

2351 (62.2)

1357 (61.5)

992 (63.3)

2 (50.0)

Female

1427 (37.8)

851 (38.5)

574 (36.7)

2 (50.0)

Age (year)

< 1

890 (23.6)

582 (26.4)

308 (19.7)

0 (0)

1 - < 2

1471 (38.9)

812 (36.8)

656 (41.9)

3 (75.0)

2 - < 3

832 (22.0)

468 (21.2)

364 (23.2)

0 (0)

3 - < 4

372 (9.9)

209 (9.4)

162 (10.3)

1 (25.0)

4–11

213 (5.6)

137 (6.2)

76 (4.9)

0 (0)

Intervention

 No steroid/IVIG/Lan-Qin

415 (11.0)

368 (16.7)

47 (3.0)

0 (0)

 Steroid only

278 (7.4)

194 (8.8)

84 (5.4)

0 (0)

 IVIG only

43 (1.1)

22 (1.0)

21 (1.3)

0 (0)

 Lan-Qin only

946 (25.0)

840 (38.0)

106 (6.8)

0 (0)

 Steroid + IVIG

359 (9.5)

92 (4.2)

264 (16.9)

3 (75.0)

 Steroid + Lan-Qin

738 (19.5)

521 (23.6)

217 (13.9)

0 (0)

 IVIG + Lan-Qin

88 (2.3)

41 (1.9)

47 (3.0)

0 (0)

 Steroid + IVIG + Lan-Qin

911 (24.1)

130 (5.9)

780 (49.8)

1 (25.0)

Outcome

 Recovery

3470 (91.8)

2082 (94.3)

1387 (88.6)

0 (0)

 Death

6 (0.2)

0 (0)

2 (0.2)

4 (100)

 Self-discharge

302 (8.0)

126 (5.7)

176 (11.2)

0 (0)

 Length of hospital stay for all cases

4.70 ± 2.6

4.09 ± 1.8

5.40 ± 3.0

14.25 ± 12.0

 Length of hospital stay without self-discharged cases

4.69 ± 2.5

4.13 ± 1.7

5.49 ± 3.2

14.25 ± 12.0

  1. $data are shown as n (%). Lan-Qin was the most prescribed drug among 8 traditional Chinese herbs (TCH)