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Table 1 The characteristics, intervention, and outcome of HFMD cases (2008–2016) $

From: Hand-foot-mouth disease and use of steroids, intravenous immunoglobulin, and traditional Chinese herbs in a tertiary hospital in Shantou, China

  Total Mild cases Severe cases Very severe cases
N = 3778 n = 2208 n = 1566 n = 4
Gender Male 2351 (62.2) 1357 (61.5) 992 (63.3) 2 (50.0)
Female 1427 (37.8) 851 (38.5) 574 (36.7) 2 (50.0)
Age (year) < 1 890 (23.6) 582 (26.4) 308 (19.7) 0 (0)
1 - < 2 1471 (38.9) 812 (36.8) 656 (41.9) 3 (75.0)
2 - < 3 832 (22.0) 468 (21.2) 364 (23.2) 0 (0)
3 - < 4 372 (9.9) 209 (9.4) 162 (10.3) 1 (25.0)
4–11 213 (5.6) 137 (6.2) 76 (4.9) 0 (0)
Intervention
 No steroid/IVIG/Lan-Qin 415 (11.0) 368 (16.7) 47 (3.0) 0 (0)
 Steroid only 278 (7.4) 194 (8.8) 84 (5.4) 0 (0)
 IVIG only 43 (1.1) 22 (1.0) 21 (1.3) 0 (0)
 Lan-Qin only 946 (25.0) 840 (38.0) 106 (6.8) 0 (0)
 Steroid + IVIG 359 (9.5) 92 (4.2) 264 (16.9) 3 (75.0)
 Steroid + Lan-Qin 738 (19.5) 521 (23.6) 217 (13.9) 0 (0)
 IVIG + Lan-Qin 88 (2.3) 41 (1.9) 47 (3.0) 0 (0)
 Steroid + IVIG + Lan-Qin 911 (24.1) 130 (5.9) 780 (49.8) 1 (25.0)
Outcome
 Recovery 3470 (91.8) 2082 (94.3) 1387 (88.6) 0 (0)
 Death 6 (0.2) 0 (0) 2 (0.2) 4 (100)
 Self-discharge 302 (8.0) 126 (5.7) 176 (11.2) 0 (0)
 Length of hospital stay for all cases 4.70 ± 2.6 4.09 ± 1.8 5.40 ± 3.0 14.25 ± 12.0
 Length of hospital stay without self-discharged cases 4.69 ± 2.5 4.13 ± 1.7 5.49 ± 3.2 14.25 ± 12.0
  1. $data are shown as n (%). Lan-Qin was the most prescribed drug among 8 traditional Chinese herbs (TCH)