Dendrobium nobile Lindley and its bibenzyl component moscatilin are able to protect retinal cells from ischemia/hypoxia by dowregulating placental growth factor and upregulating Norrie disease protein

Table 4 Group names and definition of the conditions used to treat the various experimental groups of cells or animals. In vivo fluorogold RGC experiment^a

Group names	Definition of conditions of animals that received
i. Sham (n = 4; control)	sham procedure
ii. Vehicle+I/R (n = 4)	Pre-ischemic treatment with vehicle followed by I/R
iii. DNL1.0 + I/R (n = 4)	Pre-ischemic treatment with DNL1.0 followed by I/R
iv. I/R + DNL1.0 (n = 4)	I/R followed by post-ischemic treatment with DNL1.0

^aThese animals were evaluated by the fluorogold retrograde labeling for RGC. Subtotally, 16 animals were used. In total, the overall number of the animals used was 136 (=120 + 16). Pre−/post-ischemia oral gavage of 1.0 g/kg/day of DNL (DNL1.0 + I/R; I/R + DNL1.0), or the same volume of vehicle was applied

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