Dendrobium nobile Lindley and its bibenzyl component moscatilin are able to protect retinal cells from ischemia/hypoxia by dowregulating placental growth factor and upregulating Norrie disease protein

Table 1 Group names and definition of the conditions used to treat the various experimental groups of cells or animals. In vitro MTT/Western blotting experiments^a

Group names	Definition of conditions of cells that received
DMSO+DMEM (control)	DMSO in DMEM
DMSO+OGD	OGD and treatment with DMSO at 1 h pre-OGD
Pre-OGD Mos 0.1 μM	OGD and treatment with moscatilin at 1 h pre-OGD
During OGD Mos 0.1 μM	OGD and treatment with moscatilin during OGD
Post-OGD Mos 0.1 μM	OGD and treatment with moscatilin at 1 h post-OGD

^aThe number of experiments in MTT assay for cell viability (n = 6) and Western blot assay for NDP (n = 3). The test compounds were persistently included in the culture medium during the OGD period as defined. Moscatilin (0.1 μM) was kept in DMEM from the administration. Abbreviations: NDP Norrie disease protein, DMSO dimethyl sulfoxide, OGD oxygen glucose deprivation

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