Compounds | IC50 (μM)a |
---|
SK-MEL-5 | B16F10 | MCF7 | MDA-MB-231 |
---|
1 | 2.11 | 3.95 | 2.94 | 3.89 |
2 | 3.61 | 2.17 | 2.11 | 2.85 |
3 | 3.76 | 2.02 | 4.05 | 4.10 |
4 | 3.18 | 2.86 | 4.31 | 4.63 |
5 | 1.85 | 2.68 | 3.28 | 6.06 |
- aThe selectivity index is the ratio of the IC50 values of the treatments on MDCK cells to those in the cancer cell lines. SK-MEL-5 (human melanoma); B16F10 (murine melanoma); MCF-7 (human breast adenocarcinoma); MDA-MB-231 (human breast adenocarcinoma)