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Fig. 3 | BMC Complementary and Alternative Medicine

Fig. 3

From: Herbal formula Xinshuitong capsule exerts its cardioprotective effects via mitochondria in the hypoxia-reoxygenated human cardiomyocytes

Fig. 3

The mitochondrial Δψm detected by confocal laser scanning microscopy showed that the intensity of red fluorescence of JC-1 aggregates dropped by more than 80% in the model group compared to the control group. XST dose dependent increase in the red fluorescence was noted, indicating that the drug could restore the loss of mitochondrial Δψm induced by hypoxia. Morphologically, the cells in the XST-treated groups were more regular in size and shape than those in the model group (× 400). Bar graphs showed that the red/green fluorescence intensity ratio increased in a XST dose dependent manner. All samples were checked in three independent experiments with three replicates each. Data are represented as the mean ± SD (*P<0.05 vs. XST 200, 400 or 600μg/ml, **P<0.001 vs. the control group)

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