TY - STD TI - Landskron G, De la Fuente M, Thuwajit P, Thuwajit C, Hermoso MA. Chronic inflammation and cytokines in the tumor microenvironment. J Immunol Res. 2014; https://doi.org/10.1155/2014/149185. ID - ref1 ER - TY - JOUR AU - Lin, W. W. AU - Karin, M. PY - 2007 DA - 2007// TI - A cytokine-mediated link between innate immunity, inflammation, and cancer JO - J Clin Invest VL - 117 UR - https://doi.org/10.1172/JCI31537 DO - 10.1172/JCI31537 ID - Lin2007 ER - TY - JOUR AU - Tisdale, M. J. PY - 2009 DA - 2009// TI - Mechanisms of cancer cachexia JO - Physiol Rev VL - 89 UR - https://doi.org/10.1152/physrev.00016.2008 DO - 10.1152/physrev.00016.2008 ID - Tisdale2009 ER - TY - JOUR AU - Tisdale, M. J. PY - 2001 DA - 2001// TI - Loss of skeletal muscle in cancer: biochemical mechanisms JO - Front Biosci VL - 6 ID - Tisdale2001 ER - TY - JOUR AU - Inui, A. PY - 2002 DA - 2002// TI - Cancer anorexia-cachexia syndrome: current issues in research and management JO - CA Cancer J Clin VL - 52 UR - https://doi.org/10.3322/canjclin.52.2.72 DO - 10.3322/canjclin.52.2.72 ID - Inui2002 ER - TY - JOUR AU - Vlassara, H. AU - Speigel, R. J. AU - San Doval, D. AU - Cerami, A. PY - 1986 DA - 1986// TI - Reduced plasma lipoprotien lipase activity in patients with malignancy-associated weight loss JO - Horm Metab Res VL - 18 UR - https://doi.org/10.1055/s-2007-1012410 DO - 10.1055/s-2007-1012410 ID - Vlassara1986 ER - TY - JOUR AU - Lanza-Jacoby, S. AU - Lansey, S. C. AU - Miller, E. E. AU - Cleary, M. P. PY - 1984 DA - 1984// TI - Sequential changes in the activities of lipoprotien lipase and lipogenic enzymes during tumor growth in rats JO - Cancer Res VL - 44 ID - Lanza-Jacoby1984 ER - TY - JOUR AU - Thompson, M. P. AU - Cooper, S. T. AU - Parry, B. R. AU - Tuckey, J. A. PY - 1993 DA - 1993// TI - Increased expression of the mRNA for hormone-sensitive lipase in adipose tissue of cancer patients JO - Biochim Biophys Acta VL - 1180 UR - https://doi.org/10.1016/0925-4439(93)90044-2 DO - 10.1016/0925-4439(93)90044-2 ID - Thompson1993 ER - TY - JOUR AU - Lundholm, K. AU - Bennegard, K. AU - Eden, E. AU - Svaninger, G. AU - Emery, P. W. AU - Rennie, M. J. PY - 1982 DA - 1982// TI - Efflux of 3-methylhistidine from the leg in cancer patients who experience weight loss JO - Cancer Res VL - 42 ID - Lundholm1982 ER - TY - JOUR AU - Lundholm, K. AU - Bylund, A. C. AU - Holm, J. AU - Scherstén, T. PY - 1976 DA - 1976// TI - Skeletal muscle metabolism in patients with malignant tumour JO - Eur J Cancer VL - 12 UR - https://doi.org/10.1016/0014-2964(76)90036-0 DO - 10.1016/0014-2964(76)90036-0 ID - Lundholm1976 ER - TY - JOUR AU - Lecker, S. H. AU - Solomon, V. AU - Mitch, W. E. AU - Goldberg, A. L. PY - 1999 DA - 1999// TI - Muscle protein breakdown and critical role of the ubiquitin-proteasome pathway in normal and disease states JO - J Nutr VL - 129 UR - https://doi.org/10.1093/jn/129.1.227S DO - 10.1093/jn/129.1.227S ID - Lecker1999 ER - TY - JOUR AU - Anker, S. D. AU - Chua, T. P. AU - Ponikowski, P. AU - Harrington, D. AU - Swan, J. W. AU - Kox, W. J. PY - 1997 DA - 1997// TI - Hormonal changes and catabolic / anabolic imbalance in chronic heart failure and their importance for cardiac cachexia JO - Circulation VL - 96 UR - https://doi.org/10.1161/01.CIR.96.2.526 DO - 10.1161/01.CIR.96.2.526 ID - Anker1997 ER - TY - JOUR AU - Anker, S. D. AU - Rauchhaus, M. PY - 1999 DA - 1999// TI - Insights into the pathogenesis of chronic heart failure: immune activation and cachexia JO - Curr Opin Cardiol VL - 14 UR - https://doi.org/10.1097/00001573-199905000-00004 DO - 10.1097/00001573-199905000-00004 ID - Anker1999 ER - TY - JOUR AU - Mehta, V. B. AU - Hart, J. AU - Wewers, M. D. PY - 2001 DA - 2001// TI - ATP-stimulated release of interleukin (IL)-1beta and IL-18 requires priming by lipopolysaccharide and is independent of caspase-1 cleavage JO - J Biol Chem VL - 276 UR - https://doi.org/10.1074/jbc.M006814200 DO - 10.1074/jbc.M006814200 ID - Mehta2001 ER - TY - JOUR AU - Van Snick, J. PY - 1990 DA - 1990// TI - Interleukin-6: an overview JO - Annu Rev Immunol VL - 8 UR - https://doi.org/10.1146/annurev.iy.08.040190.001345 DO - 10.1146/annurev.iy.08.040190.001345 ID - Van Snick1990 ER - TY - JOUR AU - Akira, S. PY - 2003 DA - 2003// TI - Toll-like receptor signaling JO - J Biol Chem VL - 278 UR - https://doi.org/10.1074/jbc.R300028200 DO - 10.1074/jbc.R300028200 ID - Akira2003 ER - TY - JOUR AU - Janssen-Heininger, Y. M. AU - Poynter, M. E. AU - Baeuerle, P. A. PY - 2000 DA - 2000// TI - Recent advances towards understanding redox mechanisms in the activation of nuclear factor kappaB JO - Free Radic Biol Med VL - 28 UR - https://doi.org/10.1016/S0891-5849(00)00218-5 DO - 10.1016/S0891-5849(00)00218-5 ID - Janssen-Heininger2000 ER - TY - JOUR AU - Park, H. S. AU - Jung, H. Y. AU - Park, E. Y. AU - Kim, J. AU - Lee, W. J. AU - Bae, Y. S. PY - 2004 DA - 2004// TI - Cutting edge: direct interaction of TLR4 with NAD(P)H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF-kappaB JO - J Immunol VL - 173 UR - https://doi.org/10.4049/jimmunol.173.6.3589 DO - 10.4049/jimmunol.173.6.3589 ID - Park2004 ER - TY - JOUR AU - Asehnoune, K. AU - Strassheim, D. AU - Mitra, S. AU - Kim, J. Y. AU - Abraham, E. PY - 2004 DA - 2004// TI - Involvement of reactive oxygen species in toll-like receptor 4-dependent activation of NF-kappa B JO - J Immunol VL - 172 UR - https://doi.org/10.4049/jimmunol.172.4.2522 DO - 10.4049/jimmunol.172.4.2522 ID - Asehnoune2004 ER - TY - JOUR AU - Cornelius, P. AU - Enerback, S. AU - Bjursell, G. AU - Olivecrona, T. AU - Pekala, P. H. PY - 1988 DA - 1988// TI - Regulation of lipoprotien lipase mRNA content in 3T3-L1 cells by tumour necrosis factor JO - Biochem J VL - 249 UR - https://doi.org/10.1042/bj2490765 DO - 10.1042/bj2490765 ID - Cornelius1988 ER - TY - JOUR AU - JM, A. ’. e. AU - Busquets, S. AU - Felipe, A. AU - FJ, L. ’. o. -. S. PY - 2005 DA - 2005// TI - Molecular mechanisms involved in muscle wasting in cancer and ageing: cachexia versus sarcopenia JO - Int J Biochem Cell Biol VL - 37 UR - https://doi.org/10.1016/j.biocel.2004.10.003 DO - 10.1016/j.biocel.2004.10.003 ID - JM2005 ER - TY - JOUR AU - Greenberg, A. S. AU - Nordan, R. P. AU - McIntosh, J. AU - Calvo, J. C. AU - Scow, R. O. AU - Jablons, D. PY - 1992 DA - 1992// TI - Interleukin 6 reduces lipoprotien lipase activity in adipose tissue of mice in vivo and in 3T3-L1 adipocytes: a possible role for interleukin 6 in cancer cachexia JO - Cancer Res VL - 52 ID - Greenberg1992 ER - TY - JOUR AU - Beutler, B. A. AU - Cerami, A. PY - 1985 DA - 1985// TI - Recombinant interleukin 1 suppresses lipoprotein lipase activity in 3T3-L1 cells JO - J Immunol VL - 135 ID - Beutler1985 ER - TY - JOUR AU - Garcia-Martinez, C. AU - Agell, N. AU - Llovera, M. AU - López-Soriano, F. J. AU - Argilés, J. M. PY - 1993 DA - 1993// TI - Tumour necrosis factor-alpha increases the ubiquitinization of rat skeletal muscle proteins JO - FEBS Lett VL - 323 UR - https://doi.org/10.1016/0014-5793(93)81341-V DO - 10.1016/0014-5793(93)81341-V ID - Garcia-Martinez1993 ER - TY - JOUR AU - Garcia-Martinez, C. AU - Llovera, M. AU - Agell, N. AU - López-Soriano, F. J. AU - Argilés, J. M. PY - 1995 DA - 1995// TI - Ubiquitin gene expession in skeletal muscle is increased during sepsis: involvement of TNF-alpha but not IL-1 JO - Biochem Biophys Res Comm VL - 217 UR - https://doi.org/10.1006/bbrc.1995.2848 DO - 10.1006/bbrc.1995.2848 ID - Garcia-Martinez1995 ER - TY - JOUR AU - Ebisui, C. AU - Tsujinaka, T. AU - Morimoto, T. AU - Kan, K. AU - Iijima, S. AU - Yano, M. PY - 1995 DA - 1995// TI - Interleukin-6 induces proteolysis by activating intracellular proteases (cathepsins B and L, proteasome) in C2C12 myotubes JO - Clin Sci VL - 89 UR - https://doi.org/10.1042/cs0890431 DO - 10.1042/cs0890431 ID - Ebisui1995 ER - TY - JOUR AU - Grivennikov, S. I. AU - Greten, F. R. AU - Karin, M. PY - 2010 DA - 2010// TI - Immunity, inflammation, and Cancer JO - Cell VL - 140 UR - https://doi.org/10.1016/j.cell.2010.01.025 DO - 10.1016/j.cell.2010.01.025 ID - Grivennikov2010 ER - TY - JOUR AU - Buck, M. AU - Chojkier, M. PY - 1996 DA - 1996// TI - Muscle wasting and dedifferentiation induced by oxidative stress in a murine model of cachexia is prevented by inhibitors of nitric oxide synthesis and antioxidants JO - EMBO J VL - 15 ID - Buck1996 ER - TY - JOUR AU - Elmore, S. PY - 2007 DA - 2007// TI - Apoptosis: a review of programmed cell death JO - Toxicol Pathol VL - 35 UR - https://doi.org/10.1080/01926230701320337 DO - 10.1080/01926230701320337 ID - Elmore2007 ER - TY - JOUR AU - Du, J. AU - Wang, X. AU - Miereles, C. AU - Bailey, J. L. AU - Debigare, R. AU - Zheng, B. PY - 2004 DA - 2004// TI - Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions JO - J Clin Invest VL - 113 UR - https://doi.org/10.1172/JCI18330 DO - 10.1172/JCI18330 ID - Du2004 ER - TY - JOUR AU - Singh, G. AU - Sharma, P. K. AU - Dudhe, R. AU - Singh, S. PY - 2010 DA - 2010// TI - Biological activities of Withania somnifera. Ann JO - Biol Res VL - 1 ID - Singh2010 ER - TY - JOUR AU - Budhiraja, R. D. AU - Krishan, P. AU - Sudhir, S. PY - 2000 DA - 2000// TI - Biological activity of withanolides JO - J Sci Ind Res VL - 59 ID - Budhiraja2000 ER - TY - JOUR AU - Malik, F. AU - Singh, J. AU - Khajuria, A. AU - Suri, K. A. AU - Satti, N. K. AU - Singh, S. PY - 2007 DA - 2007// TI - A standardized root extract of Withania somnifera and its major constituent withanolide-a elicit humoral and cell-mediated immune responses by up regulation of Th1-dominant polarization in BALB/c mice JO - Life Sci VL - 80 UR - https://doi.org/10.1016/j.lfs.2007.01.029 DO - 10.1016/j.lfs.2007.01.029 ID - Malik2007 ER - TY - JOUR AU - Sudhir, S. AU - Budhiraja, R. D. AU - Miglani, G. P. AU - Arora, B. AU - Gupta, L. C. AU - Garg, K. N. PY - 1986 DA - 1986// TI - Pharmacological studies on leaves of Withania somnifera JO - Planta Med VL - 1 UR - https://doi.org/10.1055/s-2007-969072 DO - 10.1055/s-2007-969072 ID - Sudhir1986 ER - TY - STD TI - Thakur RS, Puri HS, Husain A. Major medicinal plants of India. New Delhi: central Institute of Medicinal and Aromatic. Plants. 1986; ID - ref35 ER - TY - JOUR AU - Agarwal, R. AU - Diwanay, S. AU - Patki, P. S. AU - Patwardhan, B. PY - 1999 DA - 1999// TI - Studies on immunomodulatory activity of Withania somnifera (Ashwagandha) extracts in experimental immune inflammation JO - J Ethnopharmacol VL - 67 UR - https://doi.org/10.1016/S0378-8741(99)00065-3 DO - 10.1016/S0378-8741(99)00065-3 ID - Agarwal1999 ER - TY - JOUR AU - Kamath, R. AU - Satish Rao, B. S. AU - Uma Devi, P. PY - 1999 DA - 1999// TI - Response of a mouse fibrosarcoma to withferin a and radiation JO - Pharm Pharmacol Commun VL - 5 UR - https://doi.org/10.1211/146080899128734866 DO - 10.1211/146080899128734866 ID - Kamath1999 ER - TY - JOUR AU - Malik, F. AU - Kumar, A. AU - Bhushan, S. AU - Mondhe, D. M. AU - Pal, H. C. AU - Sharma, R. PY - 2009 DA - 2009// TI - Immune modulation and apoptosis induction: two sides of antitumoural activity of a standardized herbal formulation of Withania somnifera JO - Eur J Cancer VL - 45 UR - https://doi.org/10.1016/j.ejca.2009.01.034 DO - 10.1016/j.ejca.2009.01.034 ID - Malik2009 ER - TY - JOUR AU - Rosario, J. C. J. AU - Josephine, R. M. PY - 2015 DA - 2015// TI - A review on traditional medicinal plants for anti-cancerous activity JO - Int J Recent Sci Res VL - 6 ID - Rosario2015 ER - TY - BOOK AU - Van Wyk, B. -. E. AU - van Oudshoorn, B. AU - Gericke, N. PY - 2009 DA - 2009// TI - Medicinal plants of South Africa PB - Briza Publications CY - Pretoria ID - Van Wyk2009 ER - TY - JOUR AU - Muralikrishnan, G. AU - Amanullah, S. AU - Basha, M. I. AU - Dinda, A. K. AU - Shakeel, F. PY - 2010 DA - 2010// TI - Modulating effect of Withania somnifera on TCA cycle enzymes and electron transport chain in azoxymethane-induced colon cancer in mice JO - Immunopharmacol Immunotoxicol VL - 32 UR - https://doi.org/10.3109/08923970903581540 DO - 10.3109/08923970903581540 ID - Muralikrishnan2010 ER - TY - JOUR AU - McIlwain, D. R. AU - Berger, T. AU - Mak, T. W. PY - 2013 DA - 2013// TI - Caspase functions in cell death and disease JO - Cold Spring Harb Perspect Biol VL - 5 UR - https://doi.org/10.1101/cshperspect.a008656 DO - 10.1101/cshperspect.a008656 ID - McIlwain2013 ER - TY - JOUR AU - Rasool, M. AU - Varalakshmi, P. PY - 2006 DA - 2006// TI - Immunomodulatory role of Withania somnifera root powder on experimental induced inflammation: an in vivo and in vitro study JO - Vasc Pharmacol VL - 44 UR - https://doi.org/10.1016/j.vph.2006.01.015 DO - 10.1016/j.vph.2006.01.015 ID - Rasool2006 ER - TY - JOUR AU - Dhanani, T. AU - Shah, S. AU - Gajbhiye, N. A. AU - Kumar, S. PY - 2017 DA - 2017// TI - Effect of extraction methods on yield, phytochemical constituents and antioxidant activity of Withania somnifera JO - Arab J Chem VL - 10 UR - https://doi.org/10.1016/j.arabjc.2013.02.015 DO - 10.1016/j.arabjc.2013.02.015 ID - Dhanani2017 ER - TY - JOUR AU - Dhuley, J. N. PY - 1997 DA - 1997// TI - Effect of some Indian herbs on macrophage functions in ochratoxin a treated mice JO - J Ethnopharmacol VL - 58 UR - https://doi.org/10.1016/S0378-8741(97)00072-X DO - 10.1016/S0378-8741(97)00072-X ID - Dhuley1997 ER - TY - JOUR AU - Zechner, R. AU - Newman, T. C. AU - Sherry, B. AU - Cerami, A. AU - Breslow, J. L. PY - 1988 DA - 1988// TI - Recombinant human cachectin/tumor necrosis factor but not interleukin-1 alpha downregulates lipoprotien lipase gene expression at the transcriptional level in mouse 3T3-L1 adipocytes JO - Mol Cell Biol VL - 8 UR - https://doi.org/10.1128/MCB.8.6.2394 DO - 10.1128/MCB.8.6.2394 ID - Zechner1988 ER - TY - JOUR AU - Llovera, M. AU - Garcia-Martinez, C. AU - Agell, N. AU - López-Soriano, F. J. AU - Argilés, J. M. PY - 1997 DA - 1997// TI - TNF can directly induce the expression of ubiquitin-dependent proteolytic system in rat soleus muscles JO - Biochem Biophys Res Commun VL - 230 UR - https://doi.org/10.1006/bbrc.1996.5827 DO - 10.1006/bbrc.1996.5827 ID - Llovera1997 ER - TY - JOUR AU - Russell, S. T. AU - Rajani, S. AU - Dhadda, R. S. AU - Tisdale, M. J. PY - 2009 DA - 2009// TI - Mechanism of induction of muscle protein loss by hyperglycaemia JO - Exp Cell Res VL - 315 UR - https://doi.org/10.1016/j.yexcr.2008.10.002 DO - 10.1016/j.yexcr.2008.10.002 ID - Russell2009 ER - TY - JOUR AU - Guttridge, D. C. AU - Mayo, M. W. AU - Madrid, L. V. AU - Wang, C. Y. AU - Baldwin, A. S. J. PY - 2000 DA - 2000// TI - NF-κB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia JO - Science VL - 289 UR - https://doi.org/10.1126/science.289.5488.2363 DO - 10.1126/science.289.5488.2363 ID - Guttridge2000 ER - TY - JOUR AU - Fang, Y. Z. AU - Yang, S. AU - Wu, G. PY - 2002 DA - 2002// TI - Free radicals, antioxidants, and nutrition JO - Nutrition VL - 18 UR - https://doi.org/10.1016/S0899-9007(02)00916-4 DO - 10.1016/S0899-9007(02)00916-4 ID - Fang2002 ER - TY - JOUR AU - Wang, X. AU - Hu, Z. AU - Hu, J. AU - Du, J. AU - Mitch, W. E. PY - 2006 DA - 2006// TI - Insulin resistance accelerates muscle protein degradation: activation of the ubiquitin– proteasome pathway by defects in muscle cell signaling JO - Endocrinology VL - 147 UR - https://doi.org/10.1210/en.2006-0251 DO - 10.1210/en.2006-0251 ID - Wang2006 ER -