Antischistosomal and anti-inflammatory activity of garlic and allicin compared with that of praziquantel in vivo

Table 3 Determination of serum biochemical parameters

Parameter	Group	N	Min.	Max.	Mean ± S.D.	P value^a	P value^b
ALT (IU/L)	Positive Control	20	160.00	170.00	164.00 ± 4.32		0.001^*
	Pre-garlic	20	33.00	55.00	43.50 ± 9.33	0.001^*
	Pre-allicin	20	44.00	60.00	51.50 ± 7.72	0.001^*
	Garlic	20	37.00	42.00	39.25 ± 2.22	0.001^*
	Allicin	20	53.00	88.00	73.00 ± 14.58	0.001^*
	Praziquantel	20	88.00	106.00	94.00 ± 8.16	0.001^*
AST (IU/L)	Positive Control	20	251.00	354.00	291.00 ± 44.77		0.001^*
	Pre-garlic	20	98.00	115.00	105.00 ± 7.26	0.001^*
	Pre-allicin	20	97.00	103.00	100.00 ± 2.58	0.001^*
	Garlic	20	90.00	101.00	94.00 ± 4.83	0.001^*
	Allicin	20	92.00	123.00	107.25 ± 16.01	0.001^*
	Praziquantel	20	101.00	138.00	118.25 ± 18.06	0.001^*

^aP value between positive control group and the other groups using Dunnett’s test for multiple comparisons
^bP value among all groups using one-way ANOVA
^*Indicates a significant difference between the group and the positive control

ISSN: 2662-7671