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Fig. 1 | BMC Complementary and Alternative Medicine

Fig. 1

From: Total Saikosaponins of Bupleurum yinchowense reduces depressive, anxiety-like behavior and increases synaptic proteins expression in chronic corticosterine-treated mice

Fig. 1

The schematic representation of experiment 2 design. Male C57BL/6 J mice were divided 4 groups: Control, CORT, Citalopram (10 mg/kg) and TSS (25 mg/kg). Vehicle and corticosterone were delivered for 5 weeks and continued through the behavior testing period. After 3 weeks of drug-free exposure to CORT administration, TSS and citalopram were given intragastrically once a day for 2 weeks and continued through the behavior testing period. OFT, EPM, NSFT and FST were performed. After behavior tests, the mice were sacrificed for western blot essay or immunohistochemistry analysis

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