Fig. 7From: 4-Acetylantroquinonol B inhibits lipopolysaccharide-induced cytokine release and alleviates sepsis through of MAPK and NFκB suppressionThe protective effects of 4AAQB on survival rate, cytokine production and tissue inflammation induced by CLP operation in vivo. Mice were administered with 4AAQB (0.3 and 3 mg/kg, i.p., n = 8) in DMSO or DMSO (CTL, n = 13) for 30 min, and then conducted CLP operation. a Survival was monitored for up to 10 days. Values are presented as mean + S.E.M. *p < 0.05 as compared with the LPS-activated group. b Mice were anesthetized and blood was collected for serum isolation 24 h after CLP operation, and concentration of cytokines was measured by ELISA. Values are presented mean + S.E.M. and *p < 0.05 compared with LPS-treated control groupBack to article page