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Table 3 Half maximal inhibitory concentration (IC50) and selectivity index (SI) on DENV2 replication of methanolic extracts at 60 and 85 °C and the T. officinale and U. dioica fractions obtained by silica gel chromatography

From: Taraxacum officinale and Urtica dioica extracts inhibit dengue virus serotype 2 replication in vitro

 

IC50 (μg/ml)

CC50 (μg/ml)

SI

T. officinale (60 °C)

132.50 ± 3.25

968.38 ± 37.17

7.31

U. dioica (60 °C)

74.51 ± 1.70

702.50 ± 14.50

9.43

T. officinale (85 °C)

179.1 ± 6.56

891.92 ± 29.19

4.98

U. dioica (85 °C)

194.7 ± 3.63

669.15 ± 17.13

3.44

T. officinale F-09a

165.70 ± 3.85

925.45 ± 29.27

5.59

U. dioica F-07a

126.10 ± 2.80

758.25 ± 24.75

6.01

  1. SI was calculated by the formula: CC50/IC50
  2. aFraction number obtained by chromatography