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Table 3 Effect of ChondroT on TNF-α, IL-1β, and IL-6 levels in rats with collagenase -induced arthritis

From: Anti-osteoarthritic effects of ChondroT in a rat model of collagenase-induced osteoarthritis

Groups

TNF-α (pg/mL)

IL-1β (pg/mL)

IL-6 (pg/mL)

Intact

2.67 ± 0.37b

11.69 ± 0.42c

23.47 ± 2.28c

Control

5.48 ± 0.43a

16.06 ± 0.59a

70.45 ± 8.52a

Indomethacin

3.14 ± 0.24b

13.24 ± 0.70bc

40.67 ± 1.88b

Joins tab

2.19 ± 0.34b

12.66 ± 0.73bc

31.74 ± 1.78bc

ChondroT50

3.82 ± 0.68b

14.17 ± 0.62b

44.19 ± 4.03b

ChondroT100

2.89 ± 0.70b

13.41 ± 0.35bc

34.58 ± 1.73bc

ChondroT200

2.77 ± 0.46b

13.07 ± 0.50bc

34.40 ± 2.03bc

F Value

4.603

4.87

10.56

P Value

0.0017

0.0012

0.0001

  1. All values are mean ± standard error. Values with different superscripts within the same row are significantly different at p < 0.05 by LSD multiple range test