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Table 2 IC50 Values of 90% methanolic extracts and its derived fractions for AChE, BuChE, α– and β–Glucosidase inhibition assays

From: Phytochemical profiling and in vitro screening for anticholinesterase, antioxidant, antiglucosidase and neuroprotective effect of three traditional medicinal plants for Alzheimer’s Disease and Diabetes Mellitus dual therapy

Plant

Extract

IC50 Values (μg/mL)

AChE

BuChE

α–Glc

β–Glc

B.axillaris

90% MeOH

4.96 ± 0.96

7.5 ± 0.49

17.14 ± 1.9

25.94 ± 0.4

CHCl3

12.29 ± 2.14

9.94 ± 2.14

16.65 ± 1.99

27.38 ± 1.24

n-BuOH

67.51 ± 4.81

168.62 ± 39.5

86.61 ± 5.32

270.95 ± 34.09

H2O

136.21 ± 8.2

245.1 ± 35.2

244.66 ± 12.8

387.59 ± 37.8

H.indicus

90% MeOH

48.64 ± 11.72

3.8 ± 0.2

9.33 ± 0.2

62.91 ± 6.66

CHCl3

28.14 ± 0.9

5.16 ± 0.22

11.03 ± 0.5

87.64 ± 15.41

n-BuOH

113.49 ± 11.07

276.74 ± 13.4

220.75 ± 12.4

139.8 ± 15.73

H2O

129.43 ± 8.6

76.62 ± 4.4

70.12 ± 2.13

87.5 ± 5.10

R.mysorensis

90% MeOH

21.73 ± 0.3

6.93 ± 0.4

70.11 ± 1.9

32.26 ± 3.4

CHCl3

41.35 ± 1.6

15.86 ± 7.3

26.04 ± 0.37

25.33 ± 0.3

n-BuOH

83.55 ± 2.8

208.2 ± 22.3

125.61 ± 4.24

238.89 ± 24.88

H2O

93.67 ± 2.3

120.15 ± 14.6

360.07 ± 91.3

590.49 ± 80.9

Galantamine

0.77 ± 0.09

8.1 ± 0.02

Acarbose

117.20 ± 0.017

D-Glucono-δ-lactone

10.68 ± 0.005