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Table 5 The effect of extracts of Zanthoxylum armatum and standard drug Glibenclamide on serum urea and creatinine level in normal and diabetic mice

From: Zanthoxylum armatum DC extracts from fruit, bark and leaf induce hypolipidemic and hypoglycemic effects in mice- in vivo and in vitro study

Groups Urea (m mol/L) Creatinine (μ mol/L)
Normal 5.16 ± 0.42 28.20 ± 1.82
Diabetic 17.70 ± 0.85* 37.38 ± 0.80**
Normal Zf treated 4.88 ± 0.33 29.55 ± 1.04
Diabetic Zf treated 12.10 ± 1.52* 34.30 ± 0.69**
Normal Zb treated 4.71 ± 0.45 29.52 ± 1.06
Diabetic Zb treated 12.95 ± 0.56* 34.5 ± 0.73**
Normal Zl treated 4.13 ± 0.27 29.55 ± 1.01
Diabetic Zl treated 13.70 ± 1.44* 32.03 ± 1.33 *
Diabetic Glibenclamide treated 17.70 ± 0.85* 32.87 ± 2.37*
  1. Data represented as mean ± S.D. values of 6 animals each *p < 0.001, **p < 0.05 (One way ANOVA, Dunnet’s t-test, Graph pad prism software). Normal control was compared with normal control and extract treated. The Diabetic control was compared with diabetic extract treated and standard