Skip to main content

Advertisement

Table 2 Effect of extracts of Zanthoxylum armatum and standard drug Glibenclamide on glucose level of normal and alloxan induced diabetic mice

From: Zanthoxylum armatum DC extracts from fruit, bark and leaf induce hypolipidemic and hypoglycemic effects in mice- in vivo and in vitro study

Groups Glucose level (mg/dl)
Oth day 3rd day 6th day 9th day 12th day 15th day % variance
Normal control 110.5 ± 14 99.83 ± 17 99.33 ± 18 102.2 ± 28 107.5 ± 3 109.2 ± 2 4.69%
Diabetic control 333.7 ± 1* 344.0 ± 2* 345.3 ± 22* 335.8 ± 40* 358.0 ± 20* 374.7 ± 16* 6.80%
Normal Zf treated 111.2 ± 13 107.5 ± 15 104.5 ± 16 98.67 ± 14 98.33 ± 14 78.83 ± 34** 11.46%
Diabetic Zf treated 334.2 ± 44.6 298.0 ± 1* 255.8 ± 25* 250.0 ± 30* 234.8 ± 2* 215.8 ± 30* 16.48%
Normal Zb. Treated 114.0 ± 15. 109.7 ± 13 112.7 ± 13 101.3 ± 12 94.67 ± 10 94.5 ± 12 8.47%
Diabetic Zb treated 279.8 ± 36 265.8 ± 3* 259.2 ± 38* 252.2 ± 35* 246.3 ± 3* 239.2 ± 33* 5.65%
Normal Zl treated 106.8 ± 17 105.3 ± 15 108.8 ± 17 99.6 ± 14 100.2 ± 11 98.83 ± 14 4.09%
Diabetic Zl treated 325.2 ± 26 234.0 ± 3* 188.8 ± 36* 154.0 ± 23* 147.5 ± 2* 123.7 ± 18* 37.95%
Diabetic Glibenclamide treated 320.7 ± 22 271.5 ± 18* 215.7 ± 18* 154.2 ± 18* 163.0 ± 1* 136.3 ± 17* 34.84%
  1. Data represented as mean ± S.D. values of 6 animals each *p < 0.001, **p < 0.05 (One way ANOVA, Dunnet’s t-test, Graph pad prism software). Normal control was compared with normal control. and extract treated. The Diabetic control was compared with diabetic extract treated and standard