Fig. 5

SOE improves micro-architectural and behavioural parameters. a Representative 3D μCT images of tibia plateau region of different groups. b Trabecular number (Tb.N, 1/mm); (c) Trabecular Separation; (Tb.Sp, mm) (d) Open-field activity and (e) Rota rod test to examine the locomotor function and motor coordination. All values are expressed as Mean ± S.E.M. (n = 6/group); *P < 0.05, **P < 0.01, ***P < 0.001 compared to the MIA group, ^###P < 0.001 compared to the 250 mg.kg^− 1 day^− 1 dose, NS= non significant