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Table 2 Extraction yields using different solvents and their inhibition of the elastase and collagenase enzymes

From: Anti-aging potential of extracts from Sclerocarya birrea (A. Rich.) Hochst and its chemical profiling by UPLC-Q-TOF-MS

Extraction solvent used for the stems

Extraction yield (calculated from dry plant material) as w/w %

Elastase assay (% Inhibition ± SD)

Collagenase assay (% Inhibition ± SD)

Acetone

3.36

** 91.25 ± 0.11

91.17 ± 3.59

Methanol: DCM (1:1)

5.39

** 89.74 ± 0.32

93.75 ± 3.32

Ethanol

3.09

** 93.35 ± 0.89

99.08 ± 3.57

Sequential extraction with hexane

0.38

** 0

** 11.14 ± 2.51

Sequential extraction with DCM

0.22

** 6.69 ± 1.36

** 19.62 ± 2.78

Sequential extraction with ethyl acetate

0.87

** 65.02 ± 1.57

95.56 ± 1.68

Sequential extraction with methanol

8.01

99.19 ± 0.18

94.46 ± 2.31

  

Controls

 

10% MeOH

 

3.28 ± 0.34

0

10% DMSO

 

4.70 ± 0.53

1.58 ± 0.60

Elafin

 

99.21 ± 0.05

 

EDTA

  

95.66 ± 2.11

  1. ** showing a significant difference of p < 0.01 with EDTA
  2. ** showing a significant difference of p < 0.01 with elafin
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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