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Table 5 (A and B) Food consumption (g) of rats in acute and sub-acute oral toxicity tests

From: Acute and sub-acute oral toxicity of Dracaena cinnabari resin methanol extract in rats

A

Acute oral toxicity

 

Sex

Control

DC 300 mg/kg

DC 2000 mg/kg

 

P value

 Week 1

F (n = 3)

64.68 ± 2.80

63.43 ± 2.87

59.14 ± 14.67

 

0.089

 Week 2

F (n = 3)

66.16 ± 2.89

67.05 ± 5.14

63.74 ± 2.15

 

0.236

B

Sub-acute oral toxicity

 

Sex

Control

DC 500 mg/kg

DC 1000 mg/kg

DC 1500 mg/kg

P value

 Week 1

M (n = 5)

81.75 ± 1.21

81.15 ± 2.17

80.99 ± 2.55

79.26 ± 2.42

0.189

F (n = 5)

74.87 ± 2.59

72.99 ± 1.63

72.47 ± 2.28

71.55 ± 2.80

0.089

 Week 2

M (n = 5)

84.52 ± 1.13

83.93 ± 0.93

83.80 ± 1.77

82.59 ± 1.11

0.061

F (n = 5)

78.69 ± 3.26

77.56 ± 3.21

75.99 ± 3.58

74.66 ± 4.64

0.220

 Week 3

M (n = 5)

88.05 ± 2.54

87.92 ± 2.07

86.10 ± 1.94

85.19 ± 2.58

0.075

F (n = 5)

86.55 ± 3.64

86.15 ± 3.11

85.17 ± 3.75

83.21 ± 3.68

0.320

 Week 4

M (n = 5)

91.84 ± 1.60

91.08 ± 0.79

90.30 ± 1.26

90.23 ± 1.11

0.069

F (n = 5)

88.69 ± 3.66

87.35 ± 3.26

87.75 ± 3.32

87.04 ± 2.77

0.798

  1. Values expressed as a mean ± standard deviation. Sex (male, M and female, F)
  2. *p-value less than 0.05, (p < 0.05) significant value