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Table 10 (A and B) Hematological parameters of the rats in acute and sub-acute oral toxicity tests

From: Acute and sub-acute oral toxicity of Dracaena cinnabari resin methanol extract in rats

A Acute oral toxicity
Hematological Parameters Sex Control DC 300 mg/kg DC2000 mg/kg   P value
 HGB (g/L) F (n = 3) 153.00 ± 10.00 145.50 ± 9.50 149.33 ± 17.95   0.789
 WBC (10^9/L) F (n = 3) 6.83 ± 0.23 7.77 ± 0.38 8.05 ± 0.75   0.057
 Neutrophil (10^9/L) F (n = 3) 0.55 ± 0.13 0.56 ± 0.07 0.58 ± 0.14   0.961
 Lymphocyte (10^9/L) F (n = 3) 6.39 ± 0.87 6.72 ± 1.15 7.29 ± 0.52   0.498
 Monocyte (10^9/L) F (n = 3) 0.14 ± 0.03 0.15 ± 0.02 0.18 ± 0.3   0.228
 Eosinophil (10^9/L) F (n = 3) 0.08 ± 0.02 0.10 ± 0.02 0.11 ± 0.02   0.125
 Basophil (10^9/L) F (n = 3) 0.02 ± 0.01 0.03 ± 0.02 0.03 ± 0.02   0.531
B Sub-acute oral toxicity
Hematological Parameters Sex Control DC 500 mg/kg DC1000 mg/kg DC1500 mg/kg P value
 HGB (g/L) M (n = 5) 149.40 ± 6.47 148.80 ± 5.40 150.40 ± 12.72 156.80 ± 12.91 0.575
F (n = 5) 156.40 ± 5.81 148.80 ± 7.82 150.60 ± 3.85 153.40 ± 5.81 0.243
 WBC (10^9/L) M (n = 5) 9.22 ± 1.03 9.30 ± 2.45 9.46 ± 1.33 9.56 ± 3.67 0.996
F (n = 5) 6.86 ± 0.59 7.40 ± 1.15 7.38 ± 0.93 7.82 ± 0.81 0.431
 Neutrophil (10^9/L) M (n = 5) 0.98 ± 0.12 1.01 ± 0.16 1.03 ± 0.18 1.14 ± 0.30 0.626
F (n = 5) 0.81 ± 0.21 0.77 ± 0.11 0.87 ± 0.17 0.89 ± 0.14 0.646
 Lymphocyte (10^9/L) M (n = 5) 9.66 ± 2.12 9.64 ± 1.67 10.39 ± 1.99 10.77 ± 2.08 0.753
F (n = 5) 8.22 ± 1.07 8.44 ± 1.22 8.67 ± 1.00 9.20 ± 1.14 0.564
 Monocyte (10^9/L) M (n = 5) 0.16 ± 0.02 0.15 ± 0.02 0.17 ± 0.04 0.19 ± 0.04 0.411
F (n = 5) 0.17 ± 0.03 0.16 ± 0.03 0.18 ± 0.02 0.18 ± 0.03 0.623
 Eosinophil (10^9/L) M (n = 5) 0.08 ± 0.02 0.09 ± 0.02 0.10 ± 0.02 0.10 ± 0.03 0.388
F (n = 5) 0.08 ± 0.01 0.09 ± 0.02 0.07 ± 0.03 0.10 ± 0.02 0.215
 Basophil (10^9/L) M (n = 5) 0.06 ± 0.2 0.04 ± 0.03 0.04 ± 0.03 0.04 ± 0.03 0.537
F (n = 5) 0.02 ± 0.02 0.03 ± 0.02 0.03 ± 0.02 0.04 ± 0.02 0.397
  1. Values expressed as a mean ± standard deviation. Sex (male, M and female, F)
  2. *p-value less than 0.05, (p < 0.05) significant value