Skip to main content

Table 2 Anti-inflammatory effects of the methanol extract of the Baccaurea ramiflora pulp and seed on carrageenan induced paw edema in mice

From: Screening of Baccaurea ramiflora (Lour.) extracts for cytotoxic, analgesic, anti-inflammatory, neuropharmacological and antidiarrheal activities

Group

Dose

Oedema diameter (mm)

Inhibition (%)

1 h

2 h

3 h

4 h

1 h

2 h

3 h

4 h

Negative Control (1% tween 80 in water)

–

4.66 ± 0.84

4.36 ± 0.66

4.28 ± 0.40

4.02 ± 0.43

–

–

–

–

Positive control (Ibuprofen)

10 mg/kg

2.46 ± 0.42*

1.92 ± 0.44*

1.44 ± 0.39*

1.02 ± 0.36*

47.21

56

66.4

74.62

MEBRP

100 mg/kg

3.64 ± 0.51*

3.44 ± 0.44*

3.08 ± 0.52*

2.76 ± 0.46*

21.9

21.10

28.03

31.34

MEBRP

200 mg/kg

3.28 ± 0.41*

3.12 ± 0.50*

2.74 ± 0.57*

2.34 ± 0.49*

29.61

28.44

36

42

MEBRS

100 mg/kg

3.8 ± 0.42*

3.4 ± 0.50*

2.96 ± 0.23*

2.38 ± 0.48*

18.5

22.08

30.84

40.80

MEBRS

200 mg/kg

3.44 ± 0.40*

2.82 ± 0.38*

2.34 ± 0.49*

1.8 ± 0.27*

26.18

35.32

45.33

55.22

  1. Values are means ± S.E.M. of five mice (n = 5)
  2. *p < 0.05 considered as significant compared to control (One way ANOVA followed by Dunnett’s test). Control mice received vehicle (1% Tween 80 in water); positive control group received Ibuprofen 10 mg/kg body weight; MEBRP and MEBRS treated groups were administered with 100 and 200 mg/kg body weight (p.o.), respectively