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Table 2 Anti-inflammatory effects of the methanol extract of the Baccaurea ramiflora pulp and seed on carrageenan induced paw edema in mice

From: Screening of Baccaurea ramiflora (Lour.) extracts for cytotoxic, analgesic, anti-inflammatory, neuropharmacological and antidiarrheal activities

Group Dose Oedema diameter (mm) Inhibition (%)
1 h 2 h 3 h 4 h 1 h 2 h 3 h 4 h
Negative Control (1% tween 80 in water) 4.66 ± 0.84 4.36 ± 0.66 4.28 ± 0.40 4.02 ± 0.43
Positive control (Ibuprofen) 10 mg/kg 2.46 ± 0.42* 1.92 ± 0.44* 1.44 ± 0.39* 1.02 ± 0.36* 47.21 56 66.4 74.62
MEBRP 100 mg/kg 3.64 ± 0.51* 3.44 ± 0.44* 3.08 ± 0.52* 2.76 ± 0.46* 21.9 21.10 28.03 31.34
MEBRP 200 mg/kg 3.28 ± 0.41* 3.12 ± 0.50* 2.74 ± 0.57* 2.34 ± 0.49* 29.61 28.44 36 42
MEBRS 100 mg/kg 3.8 ± 0.42* 3.4 ± 0.50* 2.96 ± 0.23* 2.38 ± 0.48* 18.5 22.08 30.84 40.80
MEBRS 200 mg/kg 3.44 ± 0.40* 2.82 ± 0.38* 2.34 ± 0.49* 1.8 ± 0.27* 26.18 35.32 45.33 55.22
  1. Values are means ± S.E.M. of five mice (n = 5)
  2. *p < 0.05 considered as significant compared to control (One way ANOVA followed by Dunnett’s test). Control mice received vehicle (1% Tween 80 in water); positive control group received Ibuprofen 10 mg/kg body weight; MEBRP and MEBRS treated groups were administered with 100 and 200 mg/kg body weight (p.o.), respectively