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Fig. 6 | BMC Complementary and Alternative Medicine

Fig. 6

From: Neoboutonia melleri var velutina Prain: in vitro and in vivo hepatoprotective effects of the aqueous stem bark extract on acute hepatitis models

Fig. 6

Transaminases serum level and CYP 2E1 expression in CCl4-intoxicated mice. Animals were pretreated with NVH extract or methylprednisolone during 3 consecutive days. On the third day, acute liver injury was induced with CCl4. Mice were sacrificed 24 h after CCl4 injection. a: Dot plot showing Aspartate aminotransferase (left panel) and Alanine aminotransferase (right panel) serum level for each animal in 6 different groups. b: Correlation between Aspartate aminotransferase and Alanine aminotransferase serum level. c: CYP 2E1 expression. Bar graphs represent CYP 2E1 expression. Medians are indicated by a horizontal line. Significant Dunn’s post tests are indicated as *p < 0.05; **p < 0.01; ***p < 0.001; ns: non-significant. The p-value indicates the Mann-Whitney test; experiment conducted once; n = 10 in each group. AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; NVH: Neoboutonia velutina aqueous extract; MP: Methylprednisolone; CCl4: Carbon Tetrachloride

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