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Table 3 Micronucleus frequency [Mean ± SD]according to main individual characteristics of participants to the GIBIEX study [values at T0]

From: Clinical and genomic safety of treatment with Ginkgo biloba L. leaf extract (IDN 5933/Ginkgoselect®Plus) in elderly: a randomised placebo-controlled clinical trial [GiBiEx]

Characteristics

N

IDN 5933 [MN‰]

N

Placebo [MN‰]

p-value*

MN‰ T0

27

10.00 ± 5.32

20

9.84 ± 4.95

 
     

NS

MN‰ T1

27

12.08 ± 6.11

20

12.68 ± 7.07

 

AgeTertiles

 65–77 years

11

11.91 ± 6.75

6

8.10 ± 3.35

NS

 78–85

8

8.27 ± 3.11

7

10.84 ± 3.85

 

  ≥ 86

8

9.10 ± 4.53

7

10.33 ± 6.99

 

Sex

 Male

9

10.22 ± 4.55

9

8.73 ± 5.13

NS

 Female

18

9.89 ± 5.79

11

10.74 ± 4.84

 

Marital Status

 Unmarried

8

8.97 ± 4.37

3

5.50 ± 2.02

NS

 Married

5

9.29 ± 3.25

4

8.81 ± 3.31

 

 Divorced

1

6.11 ± −

  

 Widower

11

11.44 ± 7.02

11

11.67 ± 5.57

 

Education

 No degree/Elementary

13

11.61 ± 6.78

14

9.93 ± 5.37

NS

 Middle School

4

10.06 ± 4.75

 

 High School/University

4

10.31 ± 3.85

 

Smoking habit

 Never

13

9.28 ± 5.67

7

9.01 ± 3.56

NS

 Current Smoker

4

8.93 ± 5.52

3

8.25 ± 2.99

 

 Ex-smoker

7

10.82 ± 4.86

5

11.44 ± 6.06

 

 Not responding

3

12.59 ± 6.39

5

10.34 ± 7.05

 
  1. *t-test quantitative [for unequal variances] or Chi square qualitative [NS: p > 0.05]. Row data are shown in Additional file 3