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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: Phoyunnanin E inhibits migration of non-small cell lung cancer cells via suppression of epithelial-to-mesenchymal transition and integrin αv and integrin β3

Fig. 4

Phoyunnanin E decreases H292 and A549 cell migration: Cells were exposed to phoyunnanin E at concentrations of 1, 5 and 10 μM, and migrations at 24 and 48 h were investigated. The migrating cells were captured (a, e, and i). The relative cell migration was determined by comparing with the control (b, f, and j). Effect of phoyunnanin E on filopodia formation. After treating with non-toxic concentrations of phoyunnanin E for 48 h, cells were stained with phalloidin-rhodamine and examined using fluorescent microscopy. Filopodia characteristics are indicated by arrowheads (c, g, and k). Relative numbers of filopodia per cell in H292, A549, and HaCaT cells treated with phoyunnanin E compared with control (d, h, and l) are shown. Data are shown as mean ± SD (n = 3). * P < 0.05 versus non-treated control

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