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Fig. 4 | BMC Complementary and Alternative Medicine

Fig. 4

From: The flavonoid hesperidin exerts anti-photoaging effect by downregulating matrix metalloproteinase (MMP)-9 expression via mitogen activated protein kinase (MAPK)-dependent signaling pathways

Fig. 4

Inhibitory activity of hesperidin on the UVB-induced MMP-9 protein expression and enzyme activity in the photoaged hairless mice model. (a) Inhibition of the UVB-induced MMP-9 protein expression by hesperidin. The MMP-9 levels were determined by western blotting analysis. (b) The mRNA MMP-9 levels were determined by RT-PCR. (c) Inhibition of MMP-9 activity was measured by gelatin zymography. #P < 0.05 significant difference from control and *P < 0.05 significant difference from UVB/vehicle groups

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