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Table 1 Mean percentage DNA in tail (tail intensity) of different concentrations of extract treated and control HepG2 cells

From: Genotoxicity study of Ethiopian medicinal plant extracts on HepG2 cells

No. of experiments P. stellatum chloroform extract P. stellatum 80% Methanol extract O. integrifolia chloroform extract V. amygdalia chloroform extract
Control Concentration of extract (mg/ml) Control Concentration of extract (mg/ml) Control Concentration of extract (mg/ml) Control Concentration of extract (mg/ml)
Ethanol 1% Catechol 3 mM 0.01 0.05 0.25 0.5 1 Ethanol 1% Catechol 3 mM 0.01 0.05 0.25 0.5 DMSO 1% Catechol 3 mM 0.01 0.05 0.25 0.5 DMSO 1% Catechol 3 mM 0.01 0.05 0.25 0.5
1 2.59 2.04 2.04 2.38 2.56 2.21 5.03 2.89 2.72 2.90 2.97 2.64 5.60 2.62 2.51 3.25 2.31 2.64 3.76 1.64 1.82 2.07 2.99
2 1.80 5.88 2.13 1.95 2.93 2.00 2.05 5.18 2.51 3.07 2.21 2.90 3.08 5.18 2.16 2.43 2.54 3.00 2.63 3.36 1.61 1.57 2.59 2.55
3 1.30 3.20 1.82 2.53 2.31 2.72 2.89 2.37 5.08 2.42 2.38 2.30 2.97 2.57 3.88 1.71 2.97 3.27 3.00 2.60 4.54 1.93 1.22 1.78 3.15
4 1.47 3.16 1.54 1.72 2.67 4.51
5 3.47 5.82 3.55 3.94 4.70
Mean ± SEM 2.12 ± 0.40 4.52 ± 0.77 2.00 ± 0.09 2.02 ± 0.20 2.58 ± 0.31 2.78 ± 0.32 4.03 ± 0.57 2.21 ± 0.09 5.10 ± 0.04 2.61 ± 0.14 2.72 ± 0.20 2.47 ± 0.22 2.95 ± 0.02 2.76 ± 0.16 4.89 ± 0.52 2.16 ± 0.26 2.64 ± 0.17 3.02 ± 0.24 2.77 ± 0.23 2.62 ± 0.01 3.89 ± 0.35 1.73 ± 0.10 1.54 ± 0.17 2.15 ± 0.24 2.90 ± 0.18
p-value 1.00 0.022 0.819 0.827 0.399 0.239 0.030 1.00 0.0001 0.08 0.08 0.33 0.001 1.00 0.02 0.12 0.61 0.42 0.98 1.00 0.02 0.001 0.003 0.11 0.20