Fig. 8

Correlations between serum / blood cell concentrations of a microbial metabolite (M1) of Pycnogenol® and ADAMTS protein concentrations in serum of the patients. a. Relationship between concentration of M1 and ADAMTS-5 levels in serum (n = 23). The inverse correlation was weak, but statistically significant (r = −0.395; p = 0.016). b. Relationship between concentration of M1 in blood cells and ADAMTS-4 levels in serum (n = 23). The inverse correlation was weak, but statistically significant (r = −0.445; p = 0.033). The dotted lines symbolize the 95% CI