Fig. 6
Correlation between the MMP3 gene expression and the concentration of CTX-II in synovial fluid (SF) of patients. Gene expression is expressed as ΔCt (Ct (MMP3)-Ct (HPRT-1)). Higher expression levels of MMP3 in cartilage resulted in higher CTX-II levels in synovial fluid. The correlation was statistically significant (r =-0.548, p = 0.01; n = 23). The dotted lines symbolize the 95% CI